Download An atlas of human blastocysts by Lucinda L. Veeck, Nikica Zaninovic PDF

By Lucinda L. Veeck, Nikica Zaninovic

For those who had a accountable procedure for selecting the healthiest and so much possible conceptus from a cohort of turning out to be preembryos, exchanging greater than a unmarried one with a view to in attaining solid being pregnant premiums will be moot. someday within the not-so-distant destiny, this can be a truth. Taking a step in the direction of that destiny, An Atlas of Human Blastocysts vividly illustrates the common and unusual morphology of mammalian blastocysts. The atlas demonstrates that prolonged tradition of blastocysts is now possible within the laboratory and issues us towards the day while it is going to be attainable to choose from a few fit hatched blastocysts.

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Kinetic analysis of hexokinase in preimplantation mouse embryos has revealed that there is a switch from isoform I at the zygote to isoform II at the blastocyst stage56. Indeed, these two isoforms have differing sensitivities to phosphate, with the inhibition of isoform I by glucose-6-phosphate being overcome by phosphate57, thereby helping to explain the susceptibility of the cleavagestage embryo to inhibition by glucose. As a direct consequence of the inhibitory nature of glucose under certain culture conditions, there has been a trend to remove glucose from embryo culture media53,58.

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