Download Applications of Domino Transformations in Organic Synthesis, by Scott A. Snyder, Erick M. Carreira, Carl P. Decicco, Alois PDF

By Scott A. Snyder, Erick M. Carreira, Carl P. Decicco, Alois Fürstner, Guido Koch, Gary A. Molander, Ernst Schaumann

The quick velocity of evolution in domino, or cascade-based alterations has revolutionized the perform of chemical synthesis for the production of traditional items, designed molecules, and pharmaceuticals.


"Science of Synthesis: functions of Domino differences in natural Synthesis" explores the subject completely and systematically, serving because the foundation for useful purposes and destiny learn. The 2-volume set provides the state-of-the-art by way of layout, procedure, and experimental methods, resulting in a number of occasions being finished inside a unmarried response vessel. The content material is prepared through the middle form of response used to begin the development, be it a pericyclic response, a metal-mediated transformation, radical chemistry, or an acid-induced cascade between many others.


Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.

Show description

Read or Download Applications of Domino Transformations in Organic Synthesis, Volume 1 PDF

Similar organic books

Wastewater Bacteria (Wastewater Microbiology)

A pragmatic consultant to wastewater micro organism and the jobs they practice in wastewater treatmentCommunicating fabric in a pragmatic demeanour for operators and technicians who control and troubleshoot their wastewater therapy strategies, Wastewater micro organism discusses the potent keep an eye on and correct operation of cardio (activated sludge) and anaerobic (anaerobic digesters) organic remedy devices to make sure that an sufficient, energetic, and applicable inhabitants of micro organism is found in each one remedy unit.

Compendium of Organic Synthetic Methods Volume 11

Compendium of natural artificial equipment, quantity eleven maintains the inducement of the sequence, that's to facilitate the quest for caliber, chosen practical workforce differences, geared up by means of reacting sensible workforce of beginning fabric and practical workforce shaped, with complete references to every response.

Structure Reports: Organic Indexes

This cumulative Index of constitution stories comprises the entire constructions for the years 1913-1980 (Volumes 1 to 46B) and the authors for the most recent 10-year interval, 1971-1980 (Volumes 37B-46B).

Aliphatic Chemistry Volume 2

This product isn't to be had individually, it's only bought as a part of a collection. There are 750 items within the set and those are all bought as one entity, expert Periodical reviews offer systematic and targeted assessment insurance of growth within the significant components of chemical learn. Written via specialists of their expert fields the sequence creates a distinct carrier for the lively study chemist, delivering average severe in-depth debts of development specifically components of chemistry.

Extra resources for Applications of Domino Transformations in Organic Synthesis, Volume 1

Example text

1 Activation of Alkenes . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Activation of Alkynes . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Induction by a Pericyclic Reaction . . . . . . . . . . . . . . . . . . . . . 3 Induction by a Nucleophilic Step . . . . . . . . . . . . . . . . . . . . . . 3 318 Brook Rearrangement as the Key Step in Domino Reactions A.

6 Retro-1,3-Brook Rearrangement . . . . . . . . . . . . . . . . . . . . . . 3 1,4-Brook Rearrangement . . . . . . . . . . . . . . . . . . . . . . . . . 1 1,4-Brook Rearrangement of Silyl-Substituted Carbanions with Epoxides . . . 2 1,4-Brook Rearrangement with Dihalosilyl-Substituted Methyllithium . . . . 3 1,4-Brook Rearrangement with Allylsilanes . . . . . . . . . . . . . . . . . 4 1,4-Brook Rearrangement with Silylated Benzaldehydes .

1 Synthesis of Æ-Ylidene â-Diketones . . . . . . . . . . . . . . . . . . . . 2 Synthesis of Dienes . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Synthesis of Æ-Substituted Enones . . . . . . . . . . . . . . . . . . . . . 1 Synthesis of Æ-Halo-Substituted Enones . . . . . . . . . . . . . . . . . . 2 Synthesis of Æ-Aryl-Substituted Enones . . . . . . . . . . . . . . . . . . 4 Synthesis of Cyclopentenones .

Download PDF sample

Rated 4.60 of 5 – based on 46 votes