By Se-Kwon Kim
Biopolymers present in marine animals and vegetation provide great, mostly untapped pharmaceutical strength. study indicates that those biopolymers can be utilized to strive against numerous infectious in addition to inflammatory, oxidative, and carcinogenic elements. Chitin, Chitosan, Oligosaccharides and Their Derivatives: organic actions and purposes covers the main points of those therapeutically helpful biopolymers and their derivatives, particularly, their homes, assets, creation, and purposes in foodstuff technological know-how and know-how in addition to organic, biomedical, commercial, and agricultural fields.
Contains greater than a hundred Tables & Figures and more than 800 References
Written by means of forty foreign individuals who're major specialists within the box of average biomaterials, this publication presents an summary of the assets and construction of chitin and chitosan derivatives. It additionally covers their:
- Physical and chemical aspects
- Structural changes for biomedical applications
- Biological actions, particularly, antimicrobial, anti inflammatory, antioxidant, antihypertensive, anticancer, and antidiabetic activities
- Biomedical functions, together with their attainable implications as drug, vaccine, and gene carriers
- Industrial and agricultural applications
With their wide selection of functions, the area is asking to biopolymers to function the root for sensible meals- and drug improvement. This ebook is a vital source for these major this effort.
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Additional resources for Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications
The demineralized solids are then moved to the second column containing hot NaOH (80°C). DP time occurs for a 1–2 h duration before solids are moved on to the third column for washing. A fourth column containing hot NaOH (90°C) may be added if the objective is the production of chitosan. For the continuous enzymatic production of COS, an ultrafiltration reactor has previously been employed (Jeon and Kim 1999). While continuous processes have several advantages such as higher efficiencies and greater enzyme productivity, it was found that the high viscosity of chitosan restricted a continuous operation due to membrane fouling (Allan and Hadwiger 1979, Hadwiger and Beckman 1980, Jeon and Kim 1999).
New York: Academic Press. A. M. 1980. Chitosan as a component of pea-Fusarium solani interactions. Plant Physiol. 66:205–211. , and Brück, W. 2008. Mining marine shellfish wastes for bioactive molecules: Chitin and chitosan—Part A: Extraction methods. Biotechnol J. 3:871–877. , and Gao, P. 2006. Preparation and functional evaluation of oligopeptide-enriched hydrolysate from shrimp (Acetes chinensis) treated with crude protease from Bacillus sp. SM98011. Bioresour Technol. 97:385–390. , and Bustos, R.
However, the chemical hydrolysis of chitin or chitosan often results in low yields of COS with desired molecular weights and a large amount of monomers (Uchida et al. 1989). Additionally, toxic compounds may also be produced during the reaction, increasing the risk of environmental pollution and making a chemical production unattractive for the production of bioactive COS for human use. Therefore, enzymatic processes for COS production are now preferred (Kim and Rajapakse 2005). 4), however, residual protein often remains high and reaction times are significantly increased compared to chemical methods.