By Eberhard Passarge
Thoroughly up-to-date and revised, the 3rd variation of this acclaimed ebook effectively encompasses the basics of genetics and genomic association, integrating key molecular, theoretical, and clinical facets.
Including approximately 2 hundred didactically well-constructed and illustrated colour plates, the ebook employs a special visible strategy that makes the advanced subject material very obtainable.
Medical scholars will locate this ebook a useful pocket-sized assessment of the sphere, and it'll additionally function an invaluable reference booklet to physicians and different health-care pros.
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These larger side chains are hydrophobic (water-repellent) and make their respective amino acids less water-soluble than do hydrophilic (waterattracting) chains. Proline has an aliphatic side chain that, unlike in other amino acids, is bound to both the central carbon and to the amino group, so that a ringlike structure is formed. Aromatic side chains occur in phenylalanine (a phenyl group bound via a methylene group (—CH2—) and tryptophan (an indol ring bound via a methylene group). These amino acids are very hydrophobic.
Usage subject to terms and conditions of license. DNA as Carrier of Genetic Information Passarge, Color Atlas of Genetics © 2001 Thieme All rights reserved. Usage subject to terms and conditions of license. 35 36 Fundamentals DNA and Its Components The information for the development and specific functions of cells and tissues is stored in the genes. A gene is a portion of the genetic information, definable according to structure and function. Genes lie on chromosomes in the nuclei of cells. They consist of a complex longchained molecule, deoxyribonucleic acid (DNA).
A. Nucleotide bases The nucleotide bases in DNA are heterocyclic molecules derived from either pyrimidine or purine. Five bases occur in the two types of nucleic acids, DNA and RNA. The purine bases are adenine (A) and guanine (G). The pyrimidine bases are thymine (T) and cytosine (C) in DNA. In RNA, uracil (U) is present instead of thymine. The nucleotide bases are part of a subunit of DNA, the nucleotide. This consists of one of the four nucleotide bases, a sugar (deoxyribose), and a phosphate group.